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| |
RA (n = 177)
|
Control (n = 183)
|
p value
|
Effect size
|
|---|
|
Women
|
151 (85)
|
154 (84)
|
0.77
|
0.02
|
|
Age (years)
|
61.0 (18.0)
|
60.0 (16.0)
|
0.64
|
0.02
|
|
Height (cm)
|
155.8 (10.4)
|
157.0 (10.7)
|
0.012
|
0.13
|
|
Weight (kg)
|
54.0 (13.3)
|
54.8 (12.7)
|
0.18
|
0.07
|
|
BMI (kg/m2)
|
22.1 (4.8)
|
22.3 (4.2)
|
0.82
|
0.01
|
|
Smoking
|
51 (29)
|
26 (14)
|
0.001
|
0.18
|
|
Drinking habits
|
78 (44)
|
94 (51)
|
0.17
|
0.07
|
|
RF (IU/ml)
|
43 (98)
|
8 (3)
|
< 0.001
|
0.77
|
|
RF positive
|
134 (76)
|
20 (11)
|
< 0.001
|
0.65
|
|
Anti-CCP (U/ml)
|
67.6 (86.3)
|
0.6 (0.2)
|
< 0.001
|
0.81
|
|
Anti-CCP positive
|
152 (86)
|
5 (3)
|
< 0.001
|
0.84
|
|
RA duration (years)
|
10.4 (15.5)
|
–
|
–
|
–
|
|
csDMARD user
|
162 (92)
|
–
|
–
|
–
|
|
bDMARD user
|
104 (59)
|
–
|
–
|
–
|
|
GC user
|
47 (27)
|
–
|
–
|
–
|
|
ESR (mm/h)
|
20 (25)
|
8 (8)
|
< 0.001
|
0.41
|
|
MMP-3 (ng/ml)
|
64.5 (66.6)
|
43.0 (23.3)
|
< 0.001
|
0.36
|
|
hs-CRP (mg/l)
|
0.11 (0.38)
|
0.03 (0.05)
|
< 0.001
|
0.44
|
|
mHAQ-DI
|
0.25 (0.88)
|
–
|
–
|
–
|
|
TJC
|
2 (5)
|
–
|
–
|
–
|
|
SJC
|
0 (2)
|
–
|
–
|
–
|
|
Patient VAS
|
28 (40)
|
–
|
–
|
–
|
|
DAS28-ESR
|
3.4 (2.1)
|
–
|
–
|
–
|
- In age, height, weight, BMI, RF, anti-CCP, RA duration, ESR, MMP-3, hs-CRP, mHAQ-DI, TJC, SJC, patient VAS, and DAS28-ESR, data are shown as median (interquartile range) and other categorical data were shown as patient number (%). bDMARDs biological disease-modifying antirheumatic drugs, BMI body mass index, CCP anti-cyclic citrullinated peptide antibody, csDMARDs conventional synthetic disease-modifying antirheumatic drugs, DAS28-ESR disease activity scores in 28 joints using erythrocyte sedimentation rates, E-DII energy-adjusted dietary inflammatory index, GC glucocorticoid, hs-CRP high-sensitivity C-reactive protein, mHAQ-DI modified health assessment questionnaire disability index, MMP matrix metalloproteinase, RA rheumatoid arthritis, RF rheumatoid factor, SJC swollen joint count, TJC tender joint count, VAS visual analog scale
